As years go by, her cultural heritage has significantly influenced her work: "For me, the work that I produce is a love letter between myself and my ancestry, and looking at the inheritance that they’ve given me. It’s a past, future and present conversation that I’m constantly having." Her sustainable textiles play an important role in uncovering the artistry of African prints through a contemporary design. In parallel, the clothing is also appreciated as art by various institutions such as the Smithsonian Museum of African Art in Washington.

Sindiso Khumalo studied architecture at the University of Cape Town before moving to London, where she completed her study in textile design. She founded her eponymous label in 2012, focusing on the creation of sustainable textiles with a strong emphasis on African storytelling. The textiles of her collections are designed by hand through watercolors and collage. Over the years, she has developed a unique visual voice, which draws upon her Zulu and Ndebele heritage.