Mutu uses various ways of representing women, mainly depicted in a seemingly sensual pose, to bring about discussion of their hyper-objectification. With the use of mythical imagery, she intent to help women to embrace their own imperfections and become more accepting of others flaws instead of being influenced by the perfection as it is presented in today’s society. She purposefully dismantles old tropes and creatively pieces together new ones, in order to reorganize the reality that serves us unsavory images of ourselves.

Through performance, collage-paintings, video, and sculpture, Mutu continues to reflect on the human complexity and how one's physical body plays such a huge role in determining their experiences, survival, and ability to understand what that is. Her subjects have the appearance of cyborgs or hybrid-species, often altered and enhanced, while positioned to imply power as well as vulnerability. Her use of science fiction in collages such as Family Tree and the film The End of Eating Everything definitively situated Mutu in the genre of Afrofuturism.